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Conessine is a steroid alkaloid found in a number of plant species from the Apocynaceae family, including Holarrhena floribunda, Holarrhena antidysenterica and Funtumia elastica. It acts as a histamine antagonist, selective for the H3 subtype (with an affinity of pKi = 8.27; Ki = ~5 nM). It was also found to have long CNS clearance times, high blood-brain barrier penetration and high affinity for the adrenergic receptors.

Product Details:

Name: conessine

Synonyms: 

CONESSIN;

NERVINE;

ROGUESSINE;

1-Deazaadenosine;

Conessine,N,N-Dimethyl-con-5-enin-3-amine;

5-CONENIN-3BETA-DIMETHYLAMINE;

WRIGHTINE;

Con-5-enin-3-amine, N,N-dimethyl-, (3β)-;

NERIINE;

ROQUESSINE;

CAS:546-06-5

EINECS: 208-897-2

MF:C24H40N2

MW: 356.58800

Density: 1.05g/cm3

BP: 450.4?C at 760 mmHg

MP: 126-127?C

FP: 199.6?C

Purity: 97%+

Refractive index: 1.564

Storage condition: Store at RT

Stability:Stable under normal temperature and pressure

Appearance: white to tan powder

Acidity factor (pKa):10.20±0.70(笔谤别诲颈肠迟别诲)

Package: 5g, 25g, 100g, 500g, 1kg, 25kg

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